Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid-Induced Injury.

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作者： Courtney B,Ferrebee ^[1] ; Jianing,Li ^[2] ; Jamie,Haywood ^[1] ; Kimberly,Pachura ^[2] ; Brian S,Robinson ^[1] ; Benjamin H,Hinrichs ^[3] ; Rheinallt M,Jones ^[3] ; Anuradha,Rao ^[1] ; Paul A,Dawson ^[1]

作者单位： Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Emory University, Atlanta, Georgia. ^[1] Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina. ^[2] Department of Pathology, Emory University, Atlanta, Georgia. ^[3] Children's Healthcare of Atlanta, Atlanta, Georgia. ^[4]

关键词 ARE, anti-oxidant response element Asbt, apical sodium-dependent bile acid transporter CDCA, chenodeoxycholic acid Drosophila FGF, fibroblast growth factor FXR, farnesoid X receptor GAPDH, glyceraldehyde-3-phosphate dehydrogenase GFP, green fluorescence protein GSH, reduced glutathione GSSG, oxidized glutathione Ibabp, ileal bile acid binding protein Ileum NEC, necrotizing enterocolitis Neonate Nox, reduced nicotinamide adenine dinucleotide phosphate oxidase Nrf2, nuclear factor (erythroid-derived 2)-like 2 Nuclear Factor Erythroid-Derived 2-Like 2 Ost, organic solute transporter PBS, phosphate-buffered saline ROS, reactive oxygen species Reactive Oxygen Species TNF, tumor necrosis factor TUNEL, terminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick-end labeling WT, wild type cRNA, complementary RNA mRNA, messenger RNA

DOI 10.1016/j.jcmgh.2018.01.006

PMID 29930976

发布时间 2023-09-26

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Cellular and molecular gastroenterology and hepatology

2018年5卷4期

499-522页

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Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid-Induced Injury.

Cellular and molecular gastroenterology and hepatology

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Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid-Induced Injury.

Cellular and molecular gastroenterology and hepatology

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Cellular and molecular gastroenterology and hepatology

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