Capturing the Onset of PRC2-Mediated Repressive Domain Formation.

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第一作者： Ozgur,Oksuz

第一单位： Howard Hughes Medical Institute, New York University School of Medicine, New York, NY 10016, USA; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA.

作者： Ozgur,Oksuz ^[1] ; Varun,Narendra ^[1] ; Chul-Hwan,Lee ^[1] ; Nicolas,Descostes ^[1] ; Gary,LeRoy ^[1] ; Ramya,Raviram ^[2] ; Lili,Blumenberg ^[3] ; Kelly,Karch ^[4] ; Pedro P,Rocha ^[5] ; Benjamin A,Garcia ^[4] ; Jane A,Skok ^[3] ; Danny,Reinberg ^[6]

作者单位： Howard Hughes Medical Institute, New York University School of Medicine, New York, NY 10016, USA; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA. ^[1] Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA. ^[2] Department of Pathology, New York University School of Medicine, New York, NY 10016, USA. ^[3] Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. ^[4] Department of Pathology, New York University School of Medicine, New York, NY 10016, USA; Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA. ^[5] Howard Hughes Medical Institute, New York University School of Medicine, New York, NY 10016, USA; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: danny.reinberg@nyumc.org. ^[6]

关键词 H3K27me2/3 domains JARID2 MTF2 Polycomb epigenetics nucleation spreading