Cognitive behavioural therapy with optional graded exercise therapy in patients with severe fatigue with myotonic dystrophy type 1: a multicentre, single-blind, randomised trial.

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第一作者： Kees,Okkersen

第一单位： Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, Netherlands. Electronic address: kees.okkersen@radboudumc.nl.

作者： Kees,Okkersen ^[1] ; Cecilia,Jimenez-Moreno ^[2] ; Stephan,Wenninger ^[3] ; Ferroudja,Daidj ^[4] ; Jeffrey,Glennon ^[5] ; Sarah,Cumming ^[6] ; Roberta,Littleford ^[7] ; Darren G,Monckton ^[6] ; Hanns,Lochmüller ^[8] ; Michael,Catt ^[9] ; Catharina G,Faber ^[10] ; Adrian,Hapca ^[7] ; Peter T,Donnan ^[7] ; Gráinne,Gorman ^[11] ; Guillaume,Bassez ^[4] ; Benedikt,Schoser ^[3] ; Hans,Knoop ^[12] ; Shaun,Treweek ^[13] ; Baziel G M,van Engelen ^[14] ; OPTIMISTIC consortium

作者单位： Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, Netherlands. Electronic address: kees.okkersen@radboudumc.nl. ^[1] Institute of Genetic Medicine, University of Newcastle, Newcastle, UK. ^[2] Friedrich-Baur-Institute, Department of Neurology, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany. ^[3] Neuromuscular Reference Centre, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France. ^[4] Department of Cognitive Neuroscience, Donders Institute for Brain Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, Netherlands. ^[5] Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. ^[6] Tayside Clinical Trials Unit, University of Dundee, Dundee, UK. ^[7] Institute of Genetic Medicine, University of Newcastle, Newcastle, UK; Department of Neuropediatrics and Muscle Disorders, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany; Centro Nacional de Análisis Genómico, Center for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Catalonia, Spain. ^[8] National Innovation Centre for Ageing, University of Newcastle, Newcastle, UK; Catt-Sci, Wellingborough, UK. ^[9] Department of Neurology, Maastricht University Medical Centre, Maastricht, Netherlands. ^[10] Institute of Neuroscience, University of Newcastle, Newcastle, UK. ^[11] Academic Medical Center, University of Amsterdam, Department of Medical Psychology, Amsterdam Public Health Research Institute, Amsterdam, Netherlands. ^[12] Health Services Research Unit, University of Aberdeen, Aberdeen, UK. ^[13] Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, Netherlands. ^[14]