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首页> Stem cell research> Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications.

Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications.

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作者： Songyan,Han ^[1] ; Christopher,Tan ^[2] ; Junjun,Ding ^[1] ; Jianlong,Wang ^[1] ; Avi,Ma'ayan ^[2] ; Valerie,Gouon-Evans ^[3]

作者单位： Department of Cell, Developmental and Regenerative Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. ^[1] Department of Pharmacological Science, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. ^[2] Department of Cell, Developmental and Regenerative Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: valerige@bu.edu. ^[3]

关键词 Endoderm hepatic specification Endothelial cells Epigenetic modifications Mouse embryonic stem cells VEGFR2

主题词动物(Animals);细胞分化(Cell Differentiation);胚胎干细胞(Embryonic Stem Cells);内胚层(Endoderm);内皮细胞(Endothelial Cells);后成说, 遗传(Epigenesis, Genetic);肝(Liver);小鼠(Mice);信号传导(Signal Transduction);血管内皮生长因子受体2(Vascular Endothelial Growth Factor Receptor-2)

DOI 10.1016/j.scr.2018.06.004

PMID 29936335

发布时间 2021-06-10

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Stem cell research

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