Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain.

导出原文传递

翻译打印收藏纠错

作者： Sharan K,Bagal ^[1] ; Mark,Andrews ^[2] ; Bruce M,Bechle ^[3] ; Jianwei,Bian ^[3] ; James,Bilsland ^[4] ; David C,Blakemore ^[1] ; John F,Braganza ^[5] ; Peter J,Bungay ^[6] ; Matthew S,Corbett ^[3] ; Ciaran N,Cronin ^[5] ; Jingrong Jean,Cui ^[5] ; Rebecca,Dias ^[4] ; Neil J,Flanagan ^[4] ; Samantha E,Greasley ^[5] ; Rachel,Grimley ^[4] ; Kim,James ^[7] ; Eric,Johnson ^[5] ; Linda,Kitching ^[4] ; Michelle L,Kraus ^[5] ; Indrawan,McAlpine ^[5] ; Asako,Nagata ^[5] ; Sacha,Ninkovic ^[5] ; Kiyoyuki,Omoto ^[1] ; Stephanie,Scales ^[5] ; Sarah E,Skerratt ^[1] ; Jianmin,Sun ^[3] ; Michelle,Tran-Dubé ^[5] ; Gareth J,Waldron ^[4] ; Fen,Wang ^[5] ; Joseph S,Warmus ^[3]

作者单位： Worldwide Medicinal Chemistry , Pfizer Worldwide R&D U.K. , The Portway Building, Granta Park , Cambridge CB21 6GS , U.K. ^[1] Pfizer Worldwide R&D U.K. , Sandwich , Kent CT13 9NJ , U.K. ^[2] Pfizer Worldwide R&D, Groton Laboratories , Eastern Point Road , Groton , Connecticut 06340 , United States. ^[3] Pfizer Worldwide R&D U.K. , The Portway Building, Granta Park , Cambridge CB21 6GS , U.K. ^[4] Pfizer Worldwide R&D, La Jolla Laboratories , 10770 Science Center Drive , San Diego , California 92121 , United States. ^[5] Pharmacokinetics, Dynamics & Metabolism , Pfizer Worldwide R&D U.K. , The Portway Building, Granta Park , Cambridge CB21 6GS , U.K. ^[6] Peakdale Molecular , Discovery Park House, Ramsgate Road , Sandwich CT13 9ND , U.K. ^[7]