In renal cell carcinoma the PTEN splice variant PTEN-Δ shows similar function as the tumor suppressor PTEN itself.
第一作者:
Ines,Breuksch
第一单位:
Department of Gynecology, Johannes Gutenberg University Medical Center, Langenbeckstr. 1, 55131, Mainz, Germany.;Department of Urology, Johannes Gutenberg University Medical Center, Langenbeckstr. 1, 55131, Mainz, Germany.
作者:
医学主题词
细胞凋亡(Apoptosis);癌, 肾细胞(Carcinoma, Renal Cell);细胞黏附(Cell Adhesion);细胞运动(Cell Movement);疾病恶化(Disease Progression);细胞外基质(Extracellular Matrix);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因沉默(Gene Silencing);人类(Humans);整合素类(Integrins);肾肿瘤(Kidney Neoplasms);男(雄)性(Male);中年人(Middle Aged);肿瘤转移(Neoplasm Metastasis);PTEN磷酸水解酶(PTEN Phosphohydrolase);蛋白质亚型(Protein Isoforms);RNA, 信使(RNA, Messenger);RNA, 小分子干扰(RNA, Small Interfering)
DOI
10.1186/s12964-018-0247-9
PMID
29954386
发布时间
2019-05-13
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