Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway.-论文-万方医学网

作者： Xueran,Chen ^[1] ; Shangrong,Zhang ^[2] ; Zhen,Wang ^[1] ; Fengsong,Wang ^[2] ; Xinwang,Cao ^[1] ; Quan,Wu ^[3] ; Chenggang,Zhao ^[4] ; Huihui,Ma ^[4] ; Fang,Ye ^[5] ; Hongzhi,Wang ^[1] ; Zhiyou,Fang ^[3]

作者单位： Anhui Province Key Laboratory of Medical Physics and Technology, Center of Medical Physics and Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. ^[1] Hefei Cancer Hospital, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. ^[2] University of Science and Technology of China, No. 96, Jin Zhai Road, Hefei, 230026, Anhui, China. ^[3] School of Life Science, Anhui Medical University, No. 81, Mei Shan Road, Hefei, 230032, Anhui, China. ^[4] Central Laboratory of Medical Research Center, Anhui Provincial Hospital, No. 17, Lu Jiang Road, Hefei, 230001, Anhui, China. ^[5] Department of Radiation Oncology, First Affiliated Hospital, Anhui Medical University, No. 81, Mei Shan Road, Hefei, 230032, Anhui, China. ^[6] Anhui Province Key Laboratory of Medical Physics and Technology, Center of Medical Physics and Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. z.fang@cmpt.ac.cn. ^[7] Hefei Cancer Hospital, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. z.fang@cmpt.ac.cn. ^[8]

主题词成年人(Adult);老年人(Aged);动物(Animals);癌, 肝细胞(Carcinoma, Hepatocellular);细胞系, 肿瘤(Cell Line, Tumor);疾病模型, 动物(Disease Models, Animal);上皮-间质转化(Epithelial-Mesenchymal Transition);女(雌)性(Female);人类(Humans);肝肿瘤(Liver Neoplasms);MAP激酶信号系统(MAP Kinase Signaling System);男(雄)性(Male);膜蛋白质类(Membrane Proteins);小鼠(Mice);微丝蛋白质类(Microfilament Proteins);中年人(Middle Aged);模型, 生物学(Models, Biological);肿瘤转移(Neoplasm Metastasis);肿瘤分期(Neoplasm Staging);信号传导(Signal Transduction);rho相关激酶类(rho-Associated Kinases);ρA GTP结合蛋白质(rhoA GTP-Binding Protein)

DOI 10.1186/s13046-018-0787-2

PMID 29954442

发布时间 2019-05-09

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Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway.

Journal of experimental & clinical cancer research

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Journal of experimental & clinical cancer research

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Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway.

Journal of experimental & clinical cancer research

相似文献

Journal of experimental & clinical cancer research

相关期刊

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