首页> Molecular and biochemical parasitology> Conditional knock-down of a novel coccidian protein leads to the formation of aberrant apical organelles and abrogates mature rhoptry positioning in Toxoplasma gondii.

Conditional knock-down of a novel coccidian protein leads to the formation of aberrant apical organelles and abrogates mature rhoptry positioning in Toxoplasma gondii.

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第一作者： Juliette,Morlon-Guyot

第一单位： Dynamique des Interactions Membranaires Normales et Pathologiques, UMR5235 CNRS, INSERM, Université de Montpellier, Montpellier, France.

作者： Juliette,Morlon-Guyot ^[1] ; Laurence,Berry ^[1] ; Isabelle,Sauquet ^[1] ; Gurman,Singh Pall ^[2] ; Hiba,El Hajj ^[3] ; Markus,Meissner ^[2] ; Wassim,Daher ^[4]

作者单位： Dynamique des Interactions Membranaires Normales et Pathologiques, UMR5235 CNRS, INSERM, Université de Montpellier, Montpellier, France. ^[1] Wellcome Centre for Molecular Parasitology, University of Glasgow, Glasgow, UK; Department of Veterinary Sciences, Experimental Parasitology, Ludwig-Maximilians-Universität, München, 80802, Munich, Germany. ^[2] Departments of Internal Medicine and Experimental Pathology, Immunology and Microbiology, American University of Beirut, Beirut, 1107 2020, Lebanon. ^[3] Dynamique des Interactions Membranaires Normales et Pathologiques, UMR5235 CNRS, INSERM, Université de Montpellier, Montpellier, France. Electronic address: wassim.daher@univ-montp2.fr. ^[4]

关键词 CORVET and HOPS Invasion Microneme biogenesis Rhoptry positioning Toxoplasma gondii

医学主题词基因敲低技术(Gene Knockdown Techniques);细胞器(Organelles);蛋白质相互作用图谱(Protein Interaction Mapping);原虫蛋白质类(Protozoan Proteins);弓形虫属(Toxoplasma);毒力因子类(Virulence Factors)

DOI 10.1016/j.molbiopara.2018.06.003

PMID 29958928

发布时间 2019-03-04

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