MicroRNA-199a-3p and MicroRNA-199a-5p Take Part to a Redundant Network of Regulation of the NOS (NO Synthase)/NO Pathway in the Endothelium.
作者:
主题词
血管生成抑制剂(Angiogenesis Inhibitors);动物(Animals);牛(Cattle);细胞, 培养的(Cells, Cultured);疾病模型, 动物(Disease Models, Animal);内皮细胞(Endothelial Cells);内皮, 血管(Endothelium, Vascular);酶稳定性(Enzyme Stability);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);高血压(Hypertension);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);微RNAs(MicroRNAs);新生血管化, 生理性(Neovascularization, Physiologic);一氧化氮(Nitric Oxide);一氧化氮合酶Ⅲ型(Nitric Oxide Synthase Type III);寡核苷酸类(Oligonucleotides);硫氧还原蛋白过氧化物酶类(Peroxiredoxins);磷酸肌醇3-激酶(Phosphatidylinositol 3-Kinase);磷酰化(Phosphorylation);蛋白激酶抑制剂(Protein Kinase Inhibitors);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);信号传导(Signal Transduction);血管内皮生长因子A(Vascular Endothelial Growth Factor A);血管舒张(Vasodilation)
DOI
10.1161/ATVBAHA.118.311145
PMID
29976767
发布时间
2019-12-10
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