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Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.

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作者: Jordi,Merino [1] ; Hassan S,Dashti [2] ; Sherly X,Li [3] ; Chloé,Sarnowski [1] ; Anne E,Justice [2] ; Misa,Graff [4] ; Constantina,Papoutsakis [5] ; Caren E,Smith [6] ; George V,Dedoussis [7] ; Rozenn N,Lemaitre [7] ; Mary K,Wojczynski [8] ; Satu,Männistö [9] ; Julius S,Ngwa [10] ; Minjung,Kho [11] ; Tarunveer S,Ahluwalia [12] ; Natalia,Pervjakova [13] ; Denise K,Houston [5] ; Claude,Bouchard [14] ; Tao,Huang [15] ; Marju,Orho-Melander [16] ; Alexis C,Frazier-Wood [13] ; Dennis O,Mook-Kanamori [17] ; Louis,Pérusse [18] ; Craig E,Pennell [19] ; Paul S,de Vries [20] ; Trudy,Voortman [21] ; Olivia,Li [22] ; Stavroula,Kanoni [23] ; Lynda M,Rose [24] ; Terho,Lehtimäki [25] ; Jing Hua,Zhao [26] ; Mary F,Feitosa [27] ; Jian'an,Luan [28] ; Nicola M,McKeown [29] ; Jennifer A,Smith [30] ; Torben,Hansen [31] ; Niina,Eklund [32] ; Mike A,Nalls [33] ; Tuomo,Rankinen [34] ; Jinyan,Huang [35] ; Dena G,Hernandez [4] ; Christina-Alexandra,Schulz [12] ; Ani,Manichaikul [4] ; Ruifang,Li-Gao [36] ; Marie-Claude,Vohl [15] ; Carol A,Wang [16] ; Frank J A,van Rooij [13] ; Jean,Shin [37] ; Ioanna P,Kalafati [38] ; Felix,Day [21] ; Paul M,Ridker [39] ; Mika,Kähönen [38] ; David S,Siscovick [23] ; Claudia,Langenberg [40] ; Wei,Zhao [25] ; Arne,Astrup [28] ; Paul,Knekt [41] ; Melissa,Garcia [29] ; D C,Rao [31] ; Qibin,Qi [32] ; Luigi,Ferrucci [10] ; Ulrika,Ericson [4] ; John,Blangero [34] ; Albert,Hofman [42] ; Zdenka,Pausova [35] ; Vera,Mikkilä [43] ; Nick J,Wareham [4] ; Sharon L R,Kardia [15] ; Oluf,Pedersen [44] ; Antti,Jula [13] ; Joanne E,Curran [45] ; M Carola,Zillikens [46] ; Jorma S,Viikari [47] ; Nita G,Forouhi [48] ; José M,Ordovás [23] ; John C,Lieske [49] ; Harri,Rissanen [31] ; André G,Uitterlinden [50] ; Olli T,Raitakari [32] ; Jessica C,Kiefte-de Jong [51] ; Josée,Dupuis [52] ; Jerome I,Rotter [4] ; Kari E,North [15] ; Robert A,Scott [16] ; Michael A,Province [13] ; Markus,Perola [49] ; L Adrienne,Cupples [53] ; Stephen T,Turner [54] ; Thorkild I A,Sørensen [55] ; Veikko,Salomaa [4] ; Yongmei,Liu [9] ; Yun J,Sung [56] ; Lu,Qi [57] ; Stefania,Bandinelli [58] ; Stephen S,Rich [13] ; Renée,de Mutsert [31] ; Angelo,Tremblay [53] ; Wendy H,Oddy [59] ; Oscar H,Franco [60] ; Tomas,Paus [31] ; Jose C,Florez [61] ; Panos,Deloukas [5] ; Leo-Pekka,Lyytikäinen [62] ; Daniel I,Chasman [63] ; Audrey Y,Chu [7] ; Toshiko,Tanaka [64]
作者单位: Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. [1] Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. [2] Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA. [3] MRC Epidemiology Unit, University of Cambridge, Cambridge, UK. [4] Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA. [5] Biomedical and Translational Informatics Institute, Geisinger Health Weis Center for Research, Danvilla, PA, USA. [6] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [7] Research International and Scientific Affairs, Academy of Nutrition and Dietetics, Chicago, IL, USA. [8] Nutrition and Genomics, JM-USDA-HNRCA at Tufts University, Boston, MA, USA. [9] Department of Dietetics and Nutritional Science, School of Health Science and Education, Harokopio University, Athens, Greece. [10] Departments of Medicine, University of Washington, Seattle, USA. [11] Department of Genetics, Washington University School of Medicine, Saint Louis, MO, USA. [12] National Institute for Health and Welfare, Helsinki, Finland. [13] Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. [14] Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA. [15] Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [16] Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia. [17] Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia. [18] Genomics of Common Disease, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, UK. [19] Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, NC, USA. [20] Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA. [21] Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Peking, China. [22] Department of Clinical Sciences, Lund University Diabetes Center, Lund University, Malmö, Sweden. [23] USDA/ARS Children's Nutrition Research Center, Houston, TX, USA. [24] Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands. [25] Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands. [26] Department of Kinesiology, Faculty of Medicine, Laval University, Québec, Canada. [27] Institute of Nutrition and Functional Foods, Québec, Canada. [28] School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Callaghan, Australia. [29] Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA. [30] Department of Epidemiology, Erasmus MC University Hospital, Rotterdam, The Netherlands. [31] The Hospital for Sick Children, Translational Medicine, University of Toronto, Toronto, Canada. [32] William Harvey Research Institute, Queen Mary University of London, London, UK. [33] Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. [34] Department of Clinical Chemistry, Fimlab Laboratories, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland. [35] Nutritional Epidemiology, JM-USDA-HNRCA at Tufts University, Boston, MA, USA. [36] Data Tecnica International, Glen Echo, MD, USA. [37] Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA. [38] Department of Bioinformatics, Shanghai Institute of Hematology, Shanghai, China. [39] Center for Public Health Genomics, Division of Biostatistics and Epidemiology, University of Virginia, Charlottesville, VA, USA. [40] School of Nutrition, Laval University, Québec, Canada. [41] Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. [42] New York Academy of Medicine, New York, NY, USA. [43] Department of Nutrition, Exercise, and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark. [44] Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA. [45] Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA. [46] Department of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA. [47] Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA. [48] South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, TX, USA. [49] Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. [50] Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Canada. [51] Department of Food and Environmental Sciences, Division of Nutrition, Helsinki, Finland. [52] Department of Internal Medicine, Erasmus MC University Hospital, Rotterdam, The Netherlands. [53] Division of Medicine, Turku University Hospital, Turku, Finland. [54] Department of Medicine, University of Turku, Turku, Finland. [55] Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain. [56] IMDEA Food Institute, CEI UAM + CSIC, Madrid, Spain. [57] Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA. [58] Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland. [59] Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland. [60] Global Public Health, Leiden University College, The Hague, The Netherlands. [61] Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA. [62] Departments of Pediatrics and Medicine, Division of Genomic Outcomes, Harbor-UCLA Medical Center, Torrance, CA, USA. [63] Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC, USA. [64] NHLBI Framingham Heart Study, Framingham, MA, USA. [65] Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [66] Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, NC, USA. [67] Department of Epidemiology, Tulane University, New Orleans, LA, USA. [68] Geriatric Unit, Azienda Sanitaria Firenze-ASF, Florence, Italy. [69] Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA. [70] Telethon Kids Institute, The University of Western Australia, Perth, Western Australia, Australia. [71] Menzies Institute for Medical Research, University of Tasmania, Tasmania, Australia. [72] Rotman Research Institute, University of Toronto, Toronto, Canada. [73] Department of Psychiatry and Psychology, University of Toronto, Toronto, Canada. [74] Child Mind Institute, New York, NY, USA. [75] Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia. [76] Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. [77] Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA. tanakato@mail.nih.gov. [78]
DOI 10.1038/s41380-018-0079-4
PMID 29988085
发布时间 2022-12-07
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