换一批Chronic stress as a risk factor for Alzheimer's disease: Roles of microglia-mediated synaptic remodeling, inflammation, and oxidative stress.
第一作者：
Kanchan,Bisht
第一单位：
Axe Neurosciences, CRCHU de Québec-Université Laval, Québec, QC, Canada.
作者：
关键词
ABCA7, ATP-binding cassette transporter A7AD, Alzheimer's diseaseAPOE, Apolipoprotein EAPP, amyloid precursor proteinAlzheimer's diseaseAβ, Amyloid betaBDNF, brain derived neurotrophic factorCD11b, cluster of differentiation molecule 11BCD33, cluster of differentiation 33CNS, central nervous systemCR, complement receptorCRF, corticotropin releasing factorDAM, disease associated microgliaDAP12, DNAX-activation protein 12Dark microgliaFAD, Familial Alzheimer's diseaseFCRLS, Fc receptor-like S scavenger receptorGR, glucocorticoid receptorHPA axis, hypothalamic pituitary adrenocortical axisIBA1, ionized calcium-binding adapter molecule 1IL, interleukinLTP, long-term potentiationMGnD, microglia with a neurodegenerative phenotypeMR, mineralocorticoid receptorMicrogliaMicroglial phenotypesNADPH, nicotinamide adenine dinucleotide phosphateNFT, neurofibrillary tanglesNeurodegenerationNeuroinflammationPS, presenilinROS, reactive oxygen speciesStressSynaptic remodelingTGFβ, transforming growth factor βTLR, Toll-like receptorsTMEM119, transmembrane protein 119TNFα, tumor necrosis factor-αTREM2, triggering receptor expressed in myeloid cells 2TYROBP, TYRO protein tyrosine kinase binding proteinmPFC, medial prefrontal cortex
DOI
10.1016/j.ynstr.2018.05.003
PMID
29992181
发布时间
2024-04-02
- 浏览35
Neurobiology of stress
2018年9卷
9-21页
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