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首页> Journal of cell science> FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models.

FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models.

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第一作者： Samantha J,Stehbens

第一单位： School of Biomedical Sciences, Queensland University of Technology (QUT) located at the Translational Research Institute, Woolloongabba, Brisbane, QLD 4102, Australia s.stehbens@uq.edu.au pamela.pollock@qut.edu.au.

作者： Samantha J,Stehbens ^[1] ; Robert J,Ju ^[2] ; Mark N,Adams ^[3] ; Samuel R,Perry ^[2] ; Nikolas K,Haass ^[3] ; David M,Bryant ^[3] ; Pamela M,Pollock ^[2]

作者单位： School of Biomedical Sciences, Queensland University of Technology (QUT) located at the Translational Research Institute, Woolloongabba, Brisbane, QLD 4102, Australia s.stehbens@uq.edu.au pamela.pollock@qut.edu.au. ^[1] The University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Translational Research Institute, Woolloongabba, Brisbane, QLD 4102, Australia. ^[2] School of Biomedical Sciences, Queensland University of Technology (QUT) located at the Translational Research Institute, Woolloongabba, Brisbane, QLD 4102, Australia. ^[3] Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK. ^[4] Institute of Cancer Sciences, University of Glasgow, Glasgow, G12 8QQ, UK. ^[5]

关键词 Endometrial cancer FGFR Invasion Migration Polarity

主题词生物素化作用(Biotinylation);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞极性(Cell Polarity);细胞增殖(Cell Proliferation);趋化作用(Chemotaxis);子宫内膜肿瘤(Endometrial Neoplasms);女(雌)性(Female);荧光抗体技术(Fluorescent Antibody Technique);HEK293细胞(HEK293 Cells);人类(Humans);免疫印迹法(Immunoblotting);慢病毒属(Lentivirus);突变(Mutation);受体, 成纤维细胞生长因子, 2型(Receptor, Fibroblast Growth Factor, Type 2)

DOI 10.1242/jcs.213678

PMID 30002137

发布时间 2019-10-18

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Journal of cell science

Journal of cell science

2018年131卷15期

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