换一批
换一批E47 Governs the MYC-CDKN1B/p27<sup>KIP1</sup>-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16<sup>INK4A</sup> and Wild-Type p53.
作者：
关键词
CDK, cyclin-dependent kinaseCDKN1B/p27KIP1, CDKN1B/p27Kinase Inhibitory Protein 1CDKN2A/p16INK4A, CDKN2A/p16Inhibitor of CDK 4ACEBP-α, CCAAT/enhancer binding protein alphaCENP-A, centromere protein ACIP, Cyclin-Dependent Kinase Inhibitor 1Cell CycleDDR, DNA damage responseERK, extracellular signal–regulated kinaseGO, Gene OntologyINK, Inhibitor of CDKKIP, Kinase Inhibitory ProteinMSCV, murine stem cell virusOIS, oncogene-induced senescencePCR, polymerase chain reactionPDA, pancreatic ductal adenocarcinomaPancreatic Ductal AdenocarcinomaRB, retinoblastomaRNA-seq, RNA sequencingSA-βgal, senescence-associated β-galactosidaseSKP, S-phase Kinase-associatedSenescencebHLHbHLH, basic helix-loop-helixlfdr, local false discovery ratemRNA, messenger RNAshRB, short hairpin RNA directed against RBshRNA, short hairpin RNAsi-p27, small interfering RNA directed against p27
DOI
10.1016/j.jcmgh.2018.05.002
PMID
30003124
发布时间
2023-09-26
- 浏览6
Cellular and molecular gastroenterology and hepatology
2018年6卷2期
181-198页
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