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P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes.

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作者单位: International Center for Type 1 Diabetes, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, "L. Sacco" Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy. [1] Nephrology Division, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA. [2] Heart Failure and Heart Transplant Program, Department of Experimental Diagnostic and Specialty Medicine, Alma Mater-University of Bologna, Bologna, Italy. [3] Medicine, Al-Azhar University, Cairo, Egypt. [4] Transplantation Research Center, Nephrology Division, Brigham and Women's Hospital, Boston, Massachusetts, USA. [5] Laboratorio Genetica Medica and. [6] Dipartimento Cardiovascolare, ASST Papa Giovanni XXIII, Bergamo, Italy. [7] Division of Respiratory Diseases, Boston Children's Hospital, Boston, Massachusetts, USA. [8] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [9] Department of Biomedical, Biotechnological and Translational Sciences, Unit of Pathology, University of Parma, Parma, Italy. [10] Heart Failure Center, Heart & Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA. [11] Endocrinology and Metabolism, Department of Health Science, University of Milan, ASST Santi Paolo e Carlo, Milan, Italy. [12] Department of Pediatrics, Children's Hospital Buzzi, Milan, Italy. [13] American University of Beirut, Beirut, Lebanon. [14] Department of Medicine and Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [15] Endocrinology Division, ASST Fatebenefratelli Sacco, Milan, Italy. [16]
DOI 10.1172/JCI94524
PMID 30010623
发布时间 2019-09-10
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