Genetic polymorphisms in the circumsporozoite protein of Plasmodium malariae show a geographical bias.

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作者： Naowarat,Saralamba ^[1] ; Mayfong,Mayxay ^[2] ; Paul N,Newton ^[3] ; Frank,Smithuis ^[4] ; Francois,Nosten ^[5] ; Laypaw,Archasuksan ^[3] ; Sasithon,Pukrittayakamee ^[5] ; Nicholas J,White ^[6] ; Nicholas P J,Day ^[7] ; Arjen M,Dondorp ^[7] ; Mallika,Imwong ^[8]

作者单位： Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand. ^[1] Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. ^[2] Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao PDR. ^[3] Faculty of Postgraduate Studies, University of Health Sciences, Vientiane, Lao PDR. ^[4] Centre for Tropical Medicine and Global Health, Churchill Hospital, University of Oxford, Oxford, UK. ^[5] Medical Action Myanmar, Yangon, Myanmar. ^[6] Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, OX3 7LF, UK. ^[7] Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand. ^[8] Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. ^[9] Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand. noi@tropmedres.ac. ^[10] Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. noi@tropmedres.ac. ^[11]

关键词 Circumsporozoite protein Malaria Plasmodium malariae