A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A.

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作者： Sultan,Ciftci-Yilmaz ^[1] ; Wei-Chun,Au ^[1] ; Prashant K,Mishra ^[1] ; Jessica R,Eisenstatt ^[1] ; Joy,Chang ^[1] ; Anthony R,Dawson ^[1] ; Iris,Zhu ^[2] ; Mahfuzur,Rahman ^[3] ; Sven,Bilke ^[1] ; Michael,Costanzo ^[4] ; Anastasia,Baryshnikova ^[5] ; Chad L,Myers ^[3] ; Paul S,Meltzer ^[1] ; David,Landsman ^[2] ; Richard E,Baker ^[6] ; Charles,Boone ^[4] ; Munira A,Basrai ^[7]

作者单位： Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892. ^[1] National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894. ^[2] Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minneapolis, Minnesota 55455. ^[3] Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Ontario M5S 3E1, Canada. ^[4] Lewis-Sigler Institute for Integrative Genomics, Princeton University, New Jersey 08544. ^[5] Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts 01655. ^[6] Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 basraim@mail.nih.gov. ^[7]

关键词 CENP-A Cse4 centromere chromosome segregation gene regulation histone chaperone histones kinetochore