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Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway.

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第一作者： Pengfei,Xu

第一单位： Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China.

作者： Pengfei,Xu ^[1] ; Qian,Liu ^[1] ; Yi,Xie ^[1] ; Xiaolei,Shi ^[2] ; Yunzi,Li ^[1] ; Mengna,Peng ^[1] ; Hongquan,Guo ^[3] ; Rui,Sun ^[4] ; Juanji,Li ^[1] ; Ye,Hong ^[1] ; Xinfeng,Liu ^[5] ; Gelin,Xu ^[6]

作者单位： Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China. ^[1] Kinsmen Laboratory of Neurological Research, University of British Columbia, Vancouver, British Columbia, Canada; Department of Neurology, The First Affiliated Hospital, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui 241001, China. ^[2] Department of Neurology, Jinling Hospital, Southern Medical University, Nanjing, Jiangsu 210002, China. ^[3] Department of Neurology, Jinling Clinical College of Nanjing Medical University, Nanjing, Jiangsu 210002, China. ^[4] Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China. Electronic address: xfliu2@vip.163.com. ^[5] Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China. Electronic address: gelinxu@nju.edu.cn. ^[6]

关键词 BRCA1 DNA damage Ischemia/Reperfusion NRF2 Oxidative stress