Glucosamine prevents polarization of cytotoxic granules in NK-92 cells by disturbing FOXO1/ERK/paxillin phosphorylation.
第一作者:
Janja,Božič
第一单位:
Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Ljubljana, Slovenia.;International Postgraduate School Jozef Stefan, Ljubljana, Slovenia.
作者:
主题词
乙酰葡萄糖胺(Acetylglucosamine);动物(Animals);组织蛋白酶C(Cathepsin C);细胞系(Cell Line);细胞质颗粒(Cytoplasmic Granules);膳食(Diet);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);葡糖胺(Glucosamine);人类(Humans);K562细胞(K562 Cells);杀伤细胞, 天然(Killer Cells, Natural);小鼠(Mice);显微镜检查, 共焦(Microscopy, Confocal);桩蛋白(Paxillin);磷酰化(Phosphorylation);重组蛋白质类(Recombinant Proteins);信号传导(Signal Transduction);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1371/journal.pone.0200757
PMID
30016365
发布时间
2019-01-30
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PloS one
e0200757页
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