Thrombopoietin knock-in augments platelet generation from human embryonic stem cells.

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第一作者： Leisheng,Zhang

第一单位： State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, 288 Nanjing Road, Tianjin, 300020, China.

作者： Leisheng,Zhang ^[1] ; Cuicui,Liu ^[2] ; Hongtao,Wang ^[1] ; Dan,Wu ^[2] ; Pei,Su ^[1] ; Mengge,Wang ^[2] ; Jiaojiao,Guo ^[1] ; Shixuan,Zhao ^[2] ; Shuxu,Dong ^[1] ; Wen,Zhou ^[2] ; Cameron,Arakaki ^[1] ; Xiaobing,Zhang ^[2] ; Jiaxi,Zhou ^[3]

作者单位： State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, 288 Nanjing Road, Tianjin, 300020, China. ^[1] Center for Stem Cell Medicine, Chinese Academy of Medical Sciences & Department of Stem Cells and Regenerative Medicine, Peking Union Medical College, Beijing, China. ^[2] School of Basic Medical Science and Cancer Research Institute, Central South University, Changsha, 410013, China. ^[3] Division of Regenerative Medicine MC 1528B, Department of Medicine, Loma Linda University, 11234 Anderson Street, Loma Linda, CA, 92350, USA. ^[4] State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, 288 Nanjing Road, Tianjin, 300020, China. zhoujx@ihcams.ac.cn. ^[5] Center for Stem Cell Medicine, Chinese Academy of Medical Sciences & Department of Stem Cells and Regenerative Medicine, Peking Union Medical College, Beijing, China. zhoujx@ihcams.ac.cn. ^[6]

关键词 Early hematopoiesis Human embryonic stem cells Knock-in Platelets Thrombopoietin

主题词血小板(Blood Platelets);细胞分化(Cell Differentiation);人类(Humans);血小板生成素(Thrombopoietin)

DOI 10.1186/s13287-018-0926-x

PMID 30016991

发布时间 2019-03-12

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