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Dual PD-1 and CTLA-4 Checkpoint Blockade Promotes Antitumor Immune Responses through CD4+Foxp3- Cell-Mediated Modulation of CD103+ Dendritic Cells.

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第一作者： Paul A,Beavis

第一单位： Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. phil.darcy@petermac.org paul.beavis@petermac.org.;Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Melbourne, Victoria, Australia.

作者： Paul A,Beavis ^[1] ; Melissa A,Henderson ^[2] ; Lauren,Giuffrida ^[2] ; Alexander J,Davenport ^[2] ; Emma V,Petley ^[2] ; Imran G,House ^[2] ; Junyun,Lai ^[2] ; Kevin,Sek ^[2] ; Nicole,Milenkovski ^[2] ; Liza B,John ^[2] ; Sherly,Mardiana ^[2] ; Clare Y,Slaney ^[2] ; Joseph A,Trapani ^[2] ; Sherene,Loi ^[2] ; Michael H,Kershaw ^[3] ; Nicole M,Haynes ^[2] ; Phillip K,Darcy ^[4]

作者单位： Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. phil.darcy@petermac.org paul.beavis@petermac.org.;Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Melbourne, Victoria, Australia. ^[1] Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.;Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Melbourne, Victoria, Australia. ^[2] Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.;Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Melbourne, Victoria, Australia.;Department of Pathology, University of Melbourne, Parkville, Melbourne, Victoria, Australia. ^[3] Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. phil.darcy@petermac.org paul.beavis@petermac.org.;Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Melbourne, Victoria, Australia.;Department of Pathology, University of Melbourne, Parkville, Melbourne, Victoria, Australia.;Department of Immunology, Monash University, Clayton, Melbourne, Victoria, Australia. ^[4]

医学主题词动物(Animals);抗原, CD(Antigens, CD);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);树突细胞(Dendritic Cells);肝细胞核因子3γ(Hepatocyte Nuclear Factor 3-gamma);免疫疗法(Immunotherapy);整合素α链(Integrin alpha Chains);白细胞介素12(Interleukin-12);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL)

DOI 10.1158/2326-6066.CIR-18-0291

PMID 30018045

发布时间 2021-01-03

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Cancer immunology research

2018年6卷9期

1069-1081页

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Cancer immunology research

2018年6卷9期

1069-1081页

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Dual PD-1 and CTLA-4 Checkpoint Blockade Promotes Antitumor Immune Responses through CD4<sup>+</sup>Foxp3<sup>-</sup> Cell-Mediated Modulation of CD103<sup>+</sup> Dendritic Cells.

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Dual PD-1 and CTLA-4 Checkpoint Blockade Promotes Antitumor Immune Responses through CD4<sup>+</sup>Foxp3<sup>-</sup> Cell-Mediated Modulation of CD103<sup>+</sup> Dendritic Cells.

Cancer immunology research

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Cancer immunology research

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