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Bone marrow derived mesenchymal stem cells ameliorate inflammatory response in an in vitro model of familial hemophagocytic lymphohistiocytosis 2.

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第一作者： Handan,Sevim

第一单位： Department of Biology, Faculty of Science, Hacettepe University, 06800, Ankara, Turkey. sevimh@hacettepe.edu.tr.

作者： Handan,Sevim ^[1] ; Yusuf Çetin,Kocaefe ^[2] ; Mehmet Ali,Onur ^[3] ; Duygu,Uçkan-Çetinkaya ^[4] ; Özer Aylin,Gürpınar ^[3]

作者单位： Department of Biology, Faculty of Science, Hacettepe University, 06800, Ankara, Turkey. sevimh@hacettepe.edu.tr. ^[1] Department of Medical Biology, Faculty of Medicine, Hacettepe University , 06100, Ankara, Turkey.;Department of Stem Cell Sciences, Institute of Health Sciences, Center for Stem Cell Research and Development (PEDI-STEM), Hacettepe University, 06100, Ankara, Turkey. ^[2] Department of Biology, Faculty of Science, Hacettepe University, 06800, Ankara, Turkey. ^[3] Department of Stem Cell Sciences, Institute of Health Sciences, Center for Stem Cell Research and Development (PEDI-STEM), Hacettepe University, 06100, Ankara, Turkey.;Pediatric Hematology, BMT Unit, Children's Hospital, Hacettepe University, 06100, Ankara, Turkey. ^[4]

关键词 CRISPR/Cas Familial hemophagocytic lymphohistiocytosis 2 Immune modulation Mesenchymal stem cells Perforin

医学主题词骨髓(Bone Marrow);女(雌)性(Female);人类(Humans);淋巴组织细胞增多症, 嗜血细胞性(Lymphohistiocytosis, Hemophagocytic);男(雄)性(Male);间质干细胞(Mesenchymal Stem Cells)

DOI 10.1186/s13287-018-0941-y

PMID 30021624

发布时间 2019-03-12

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