Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation.
第一作者:
James,Bagnall
第一单位:
Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
作者:
医学主题词
动物(Animals);细胞, 培养的(Cells, Cultured);HEK293细胞(HEK293 Cells);人类(Humans);炎症(Inflammation);巨噬细胞活化(Macrophage Activation);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);NF-κB(NF-kappa B);p50亚基NF-κB(NF-kappa B p50 Subunit);信号传导(Signal Transduction);单细胞分析(Single-Cell Analysis);Toll样受体4(Toll-Like Receptor 4);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1126/scisignal.aaf3998
PMID
30042130
发布时间
2025-05-30
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