论文期刊

取消

高级检索

检索历史清除

首页> Nature communications> Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID.

Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID.

导出 OA

翻译打印收藏纠错

作者： Hiroki,Sasaguri ^[1] ; Kenichi,Nagata ^[2] ; Misaki,Sekiguchi ^[3] ; Ryo,Fujioka ^[3] ; Yukio,Matsuba ^[3] ; Shoko,Hashimoto ^[3] ; Kaori,Sato ^[3] ; Deepika,Kurup ^[3] ; Takanori,Yokota ^[3] ; Takaomi C,Saido ^[4]

作者单位： Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako-shi, Saitama, 351-0198, Japan. hiroki.sasaguri@riken.jp. ^[1] Department of Neurology and Neurological Science, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, 113-8510, Japan. hiroki.sasaguri@riken.jp. ^[2] Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako-shi, Saitama, 351-0198, Japan. ^[3] Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 02138, USA. ^[4] Department of Neurology and Neurological Science, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, 113-8510, Japan. ^[5] Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako-shi, Saitama, 351-0198, Japan. takaomi.saido@riken.jp. ^[6]

主题词动物(Animals);碱基配对(Base Pairing);碱基序列(Base Sequence);胞苷脱氨酶(Cytidine Deaminase);女(雌)性(Female);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 近交ICR(Mice, Inbred ICR);小鼠, 基因敲除(Mice, Knockout);突变(Mutation);早老素1(Presenilin-1);结果可重复性(Reproducibility of Results);序列同源性, 核酸(Sequence Homology, Nucleic Acid)

DOI 10.1038/s41467-018-05262-w

PMID 30042426

发布时间 2019-07-24

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交

浏览2

Nature communications

Nature communications

2018年9卷1期

2892页

相似文献

中文期刊
外文期刊
学位论文
会议论文

特别提示：本网站仅提供医学学术资源服务，不销售任何药品和器械，有关药品和器械的销售信息，请查阅其他网站。

客服热线：4000-115-888 转3 (周一至周五：8:00至17:00)
|
客服邮箱：yiyao@wanfangdata.com.cn

违法和不良信息举报电话：4000-115-888，举报邮箱：problem@wanfangdata.com.cn，举报专区

官方微信

万方医学小程序

关于我们网站地图知识产权

北京万方数据股份有限公司

万方数据电子出版社

京ICP证010071号

京公网安备11010802020237号

京ICP备08100800号-1

违法和不良信息举报电话：4000-115-888，举报邮箱：problem@wanfangdata.com.cn，举报专区

new翻译充值订阅收藏移动端

官方微信

万方医学小程序

调查问卷