Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.

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作者： Richard C,Pelikan ^[1] ; Jennifer A,Kelly ^[1] ; Yao,Fu ^[1] ; Caleb A,Lareau ^[2] ; Kandice L,Tessneer ^[3] ; Graham B,Wiley ^[1] ; Mandi M,Wiley ^[1] ; Stuart B,Glenn ^[1] ; John B,Harley ^[1] ; Joel M,Guthridge ^[4] ; Judith A,James ^[5] ; Martin J,Aryee ^[5] ; Courtney,Montgomery ^[6] ; Patrick M,Gaffney ^[2]

作者单位： Division of Genomics and Data Sciences, Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, 73104, OK, USA. ^[1] Department of Biostatistics, Harvard T.H. Chan School of Public Health, Charlestown, 02115, MA, USA. ^[2] Department of Pathology, Harvard Medical School, Boston, 02115, MA, USA. ^[3] Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital, Cincinnati, 45229, OH, USA. ^[4] Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, 73104, OK, USA. ^[5] Departments of Medicine and Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, 73104, OK, USA. ^[6] Division of Genomics and Data Sciences, Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, 73104, OK, USA. Patrick-Gaffney@omrf.org. ^[7]