CCL20 triggered by chemotherapy hinders the therapeutic efficacy of breast cancer.-论文-万方医学网

第一作者： Weilong,Chen

第一单位： School of Life Science, The CAS Key Laboratory of Innate Immunity and Chronic Disease, University of Science & Technology of China, Hefei, Anhui, China.

作者： Weilong,Chen ^[1] ; Yuanyuan,Qin ^[1] ; Dong,Wang ^[2] ; Lei,Zhou ^[2] ; Yin,Liu ^[3] ; Sheng,Chen ^[3] ; Liang,Yin ^[4] ; Yaoxing,Xiao ^[5] ; Xiao-Hong,Yao ^[6] ; Xiaoli,Yang ^[7] ; Wei,Ma ^[7] ; Weifeng,Chen ^[8] ; Xueyan,He ^[7] ; Lixing,Zhang ^[7] ; Qifeng,Yang ^[9] ; Xiuwu,Bian ^[6] ; Zhi-Ming,Shao ^[10] ; Suling,Liu ^[7]

作者单位： School of Life Science, The CAS Key Laboratory of Innate Immunity and Chronic Disease, University of Science & Technology of China, Hefei, Anhui, China. ^[1] School of Life Science, The CAS Key Laboratory of Innate Immunity and Chronic Disease, University of Science & Technology of China, Hefei, Anhui, China.;Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences, Shanghai Medical College, Key Laboratory of Breast Cancer in Shanghai, Innovation Center for Cell Signaling Network, Cancer Institutes, Fudan University, Shanghai, China. ^[2] Department of Oncology, Department of Breast Surgery, Shanghai Medical College, Fudan University, Shanghai, China. ^[3] The department of breast surgery, The First People's Hospital of Zhenjiang City, Zhenjiang, China. ^[4] Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China. ^[5] Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, and Key Laboratory of Tumor Immunopathology, Ministry of Education of China, Chongqing, China. ^[6] Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences, Shanghai Medical College, Key Laboratory of Breast Cancer in Shanghai, Innovation Center for Cell Signaling Network, Cancer Institutes, Fudan University, Shanghai, China. ^[7] National Engineering Research Center for Functional Food, School of Food Science and Technology, Jiangnan University, Wuxi, China. ^[8] Department of Breast Surgery, Qilu Hospital, Shandong University, China. ^[9] Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences, Shanghai Medical College, Key Laboratory of Breast Cancer in Shanghai, Innovation Center for Cell Signaling Network, Cancer Institutes, Fudan University, Shanghai, China.;Department of Oncology, Department of Breast Surgery, Shanghai Medical College, Fudan University, Shanghai, China. ^[10]

医学主题词醛脱氢酶(Aldehyde Dehydrogenase);动物(Animals);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);趋化因子CCL20(Chemokine CCL20);化学疗法, 辅助(Chemotherapy, Adjuvant);疾病恶化(Disease Progression);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠(Mice);NF-κB(NF-kappa B);肿瘤干细胞(Neoplastic Stem Cells);预后(Prognosis);蛋白激酶C(Protein Kinase C);缓解诱导(Remission Induction);紫杉烷类(Taxoids);治疗结果(Treatment Outcome);增量调节(Up-Regulation);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)

DOI 10.1371/journal.pbio.2005869

PMID 30052635

发布时间 2019-05-06

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CCL20 triggered by chemotherapy hinders the therapeutic efficacy of breast cancer.

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CCL20 triggered by chemotherapy hinders the therapeutic efficacy of breast cancer.

PLoS biology

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PLoS biology

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