首页> Autophagy> ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis.

ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis.

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第一作者： Chiara,Vantaggiato

第一单位： a Scientific Institute, IRCCS E. Medea, Laboratory of Molecular Biology , Bosisio Parini , Lecco , Italy.

作者： Chiara,Vantaggiato ^[1] ; Elena,Panzeri ^[1] ; Marianna,Castelli ^[1] ; Andrea,Citterio ^[1] ; Alessia,Arnoldi ^[1] ; Filippo Maria,Santorelli ^[2] ; Rocco,Liguori ^[3] ; Marina,Scarlato ^[4] ; Olimpia,Musumeci ^[5] ; Antonio,Toscano ^[5] ; Emilio,Clementi ^[6] ; Maria Teresa,Bassi ^[1]

作者单位： a Scientific Institute, IRCCS E. Medea, Laboratory of Molecular Biology , Bosisio Parini , Lecco , Italy. ^[1] b Department of Molecular Medicine , IRCCS Fondazione Stella Maris , Calambrone, Pisa , Italy. ^[2] c Department of Biomedical and Neuromotor Sciences , University of Bologna; IRCCS Institute of Neurological Sciences , Bologna , Italy. ^[3] d Dept. of Neurosciences and Institute of Experimental Neurology (INSpe) , San Raffaele Scientific Institute , Milan , Italy. ^[4] e Department of Clinical and Experimental Medicine , University of Messina , Messina , Italy. ^[5] a Scientific Institute, IRCCS E. Medea, Laboratory of Molecular Biology , Bosisio Parini , Lecco , Italy.;f Unit of Clinical Pharmacology, CNR Institute of Neuroscience, Department of Biomedical and Clinical Sciences , University Hospital "Luigi Sacco", Università di Milano , Milan , Italy. ^[6]

关键词 AR-SPG11 AR-SPG15 RAB11 RAB5A SPG11 ZFYVE26 autophagosome-endosome fusion autophagy endocytosis