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The Sensitivity of In Vitro Permeation Tests to Chemical Penetration Enhancer Concentration Changes in Fentanyl Transdermal Delivery Systems.

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第一作者： Soo Hyeon,Shin

第一单位： Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD, 21201, USA.

作者： Soo Hyeon,Shin ^[1] ; Jukkarin,Srivilai ^[2] ; Sarah A,Ibrahim ^[3] ; Caroline,Strasinger ^[3] ; Dana C,Hammell ^[1] ; Hazem E,Hassan ^[4] ; Audra L,Stinchcomb ^[5]

作者单位： Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD, 21201, USA. ^[1] Department of Cosmetic Sciences, School of Pharmaceutical Sciences, University of Phayao, Phayao, 56000, Thailand. ^[2] Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, 20903, USA. ^[3] Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD, 21201, USA.;Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Helwan University, Cairo, Egypt. ^[4] Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD, 21201, USA. astinchc@rx.umaryland.edu. ^[5]

关键词 chemical penetration enhancer (CPE)fentanyl in vitro permeation test (IVPT)transdermal delivery system (TDS)