换一批
换一批Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept.
作者：
主题词
激活素受体,Ⅰ型(Activin Receptors, Type I);细胞系(Cell Line);结晶学, X线(Crystallography, X-Ray);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物评价, 临床前(Drug Evaluation, Preclinical);人类(Humans);蛋白激酶抑制剂(Protein Kinase Inhibitors);喹唑啉酮类(Quinazolinones);构效关系(Structure-Activity Relationship)
DOI
10.1021/acs.jmedchem.8b00782
PMID
30085668
发布时间
2024-02-10
- 浏览5
Journal of medicinal chemistry
7261-7272页
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