Phase Ib/II study of the pan-cyclin-dependent kinase inhibitor roniciclib in combination with chemotherapy in patients with extensive-disease small-cell lung cancer.

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第一作者： Byoung Chul,Cho

第一单位： Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. Electronic address: cbc1971@yuhs.ac.

作者： Byoung Chul,Cho ^[1] ; Grace K,Dy ^[2] ; Ramaswamy,Govindan ^[3] ; Dong-Wan,Kim ^[4] ; Nathan A,Pennell ^[5] ; Gerard,Zalcman ^[6] ; Benjamin,Besse ^[7] ; Joo-Hang,Kim ^[8] ; Goekben,Koca ^[9] ; Prabhu,Rajagopalan ^[10] ; Simon,Langer ^[11] ; Matthias,Ocker ^[12] ; Hendrik,Nogai ^[13] ; Fabrice,Barlesi ^[14]

作者单位： Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. Electronic address: cbc1971@yuhs.ac. ^[1] Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263, USA. Electronic address: grace.dy@roswellpark.org. ^[2] Washington University in St. Louis, 1 Brookings Dr, St. Louis, MO 63130, USA. Electronic address: rgovindan@wustl.edu. ^[3] Seoul National University Hospital, 101, Daehak-ro, Jongno-gu, Seoul 03080, Korea. Electronic address: kimdw@snu.ac.kr. ^[4] Cleveland Clinic Taussig Cancer Institute, 10201 Carnegie Ave, Cleveland, OH 4419, USA. Electronic address: penneln@ccf.org. ^[5] University Hospital, Clinical Research Center, Avenue de la Côte de Nacre, 14033 Caen, France. Electronic address: zalcman-g@chu-caen.fr. ^[6] Gustave Roussy, 114 Rue Edouard Vaillant, 94800 Villejuif, France. Electronic address: benjamin.besse@gustaveroussy.fr. ^[7] CHA Bundang Medical Center, CHA University, 222 Yatap-dong, Bundang-gu, Seongnam-shi, Gyeongghi-do, Korea. Electronic address: kim123@cha.ac.kr. ^[8] Bayer AG, Müllerstraße 178, 13353 Berlin, Germany. Electronic address: goekben.koca@bayer.com. ^[9] Bayer HealthCare Pharmaceuticals, Inc., 100 Bayer Boulevard, PO Box 915, Whippany, NJ 07981, USA. Electronic address: prabhu.rajagopalan@bayer.com. ^[10] Chrestos Concept GmbH & Co. KG, Girardetstraße 1-5, 45131 Essen, Germany. Electronic address: simon.langer.ext@bayer.com. ^[11] Bayer AG, Müllerstraße 178, 13353 Berlin, Germany. Electronic address: matthias.ocker@bayer.com. ^[12] Bayer AG, Müllerstraße 178, 13353 Berlin, Germany. Electronic address: hendrik.nogai@bayer.com. ^[13] Aix Marseille University, Jardin du Pharo, 58, bd Charles Livon, 13284 Marseille, France; Assistance Publique Hôpitaux de Marseille, 80, rue Brochier, 13005 Marseille, France; Centre d'Essais Précoces en Cancérologie de Marseille (CLIP(2)), Hôpital La Timone - Basement F, 1st Floor, 264, rue St Pierre, 13885 Marseille, France. Electronic address: fabrice.barlesi@ap-hm.fr. ^[14]

关键词 Extensive-disease small-cell lung cancer Platinum chemotherapy Roniciclib