Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells.
第一作者:
Reishi,Toshiyama
第一单位:
Departments of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.;Departments of Frontier Science for Cancer and Chemotherapy, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.;Departments of Medical Data Science, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.
作者:
医学主题词
动物(Animals);抗生素类, 抗肿瘤(Antibiotics, Antineoplastic);癌, 肝细胞(Carcinoma, Hepatocellular);细胞系, 肿瘤(Cell Line, Tumor);药物载体(Drug Carriers);药物释放系统(Drug Delivery Systems);人类(Humans);亮氨酸(Leucine);肝肿瘤(Liver Neoplasms);小鼠(Mice);肿瘤干细胞(Neoplastic Stem Cells);聚乙烯二醇类(Polyethylene Glycols);聚赖氨酸(Polylysine);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1038/s41388-018-0406-x
PMID
30089817
发布时间
2021-11-10
- 浏览6
Oncogene
244-260页
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