Interferon gamma decreases intestinal epithelial aquaporin 3 expression through downregulation of constitutive transcription.

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作者： Michael A,Peplowski ^[1] ; Michael,Dicay ^[1] ; Cristiane H,Baggio ^[1] ; Filip,Wysokinski ^[1] ; Bernard,Renaux ^[1] ; Morley D,Hollenberg ^[1] ; David,Proud ^[2] ; Wallace K,MacNaughton ^[1]

作者单位： Department of Physiology and Pharmacology, University of Calgary, Calgary, AB, Canada. ^[1] Department of Medicine, University of Calgary, Calgary, AB, Canada. ^[2] Department of Physiology and Pharmacology, University of Calgary, Calgary, AB, Canada. wmacnaug@ucalgary.ca. ^[3] Department of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, 3330 Hospital Dr NW, Calgary, AB, T2N 4N1, Canada. wmacnaug@ucalgary.ca. ^[4]

关键词 Inflammatory bowel disease Signal transducer and activator of transcription (STAT)Transcriptional repression

主题词水通道蛋白质3(Aquaporin 3);减量调节(Down-Regulation);HT29细胞(HT29 Cells);人类(Humans);干扰素γ(Interferon-gamma);肠黏膜(Intestinal Mucosa);转录, 遗传(Transcription, Genetic)

DOI 10.1007/s00109-018-1681-2

PMID 30090948

发布时间 2019-11-05

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准确一般字义偏差语意偏离译文作用小提交