Temporal and Spatial Epigenome Editing Allows Precise Gene Regulation in Mammalian Cells.

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第一作者： Cem,Kuscu

第一单位： Department of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.

作者： Cem,Kuscu ^[1] ; Rashad,Mammadov ^[1] ; Agnes,Czikora ^[1] ; Hayrunnisa,Unlu ^[2] ; Turan,Tufan ^[1] ; Natasha Lopes,Fischer ^[1] ; Sevki,Arslan ^[3] ; Stefan,Bekiranov ^[1] ; Masato,Kanemaki ^[4] ; Mazhar,Adli ^[5]

作者单位： Department of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA. ^[1] School of Medicine, Ankara University, Ankara, 06560, Turkey. ^[2] Department of Biology, Pamukkale University, Denizli, 20160, Turkey. ^[3] National Institute of Genetics and SOKENDAI, Mishima, Sizuoka, 411-8540, Japan; PRESTO, Japan Science and Technology Agency, Kawaguchi, Saitama 332-0012, Japan. ^[4] Department of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA. Electronic address: adli@virginia.edu. ^[5]

关键词 AID (auxin-inducible degron)CRISPR enhancer-like elements non-regulatory regions p300

主题词细胞系(Cell Line);E1A相关p300蛋白质(E1A-Associated p300 Protein);基因表达调控(Gene Expression Regulation);HEK293细胞(HEK293 Cells);人类(Humans);启动区, 遗传(Promoter Regions, Genetic)

DOI 10.1016/j.jmb.2018.08.001

PMID 30098338

发布时间 2024-01-04

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