Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen.

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第一作者： Karina K,Sanchez

第一单位： Nomis Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA.

作者： Karina K,Sanchez ^[1] ; Grischa Y,Chen ^[1] ; Alexandria M Palaferri,Schieber ^[1] ; Samuel E,Redford ^[2] ; Maxim N,Shokhirev ^[3] ; Mathias,Leblanc ^[4] ; Yujung M,Lee ^[2] ; Janelle S,Ayres ^[5]

作者单位： Nomis Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA. ^[1] Nomis Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA; Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92037, USA. ^[2] The Razavi Newman Integrative Genomics and Bioinformatics Core Facility of the Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA. ^[3] Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA. ^[4] Nomis Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: jayres@salk.edu. ^[5]

关键词 Citrobacter rodentium antivirulence asymptomatic persistent infections commensalism cooperative defenses dietary iron host-pathogen interactions insulin resistance