Synergistic effect of ursodeoxycholic acid on the antitumor activity of sorafenib in hepatocellular carcinoma cells via modulation of STAT3 and ERK.
第一作者:
Seulki,Lee
第一单位:
Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul 110‑799, Republic of Korea.
作者:
医学主题词
细胞凋亡(Apoptosis);印迹法, 蛋白质(Blotting, Western);癌, 肝细胞(Carcinoma, Hepatocellular);细胞存活(Cell Survival);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);Hep G2细胞(Hep G2 Cells);人类(Humans);肝肿瘤(Liver Neoplasms);磷酰化(Phosphorylation);活性氧(Reactive Oxygen Species);STAT3转录因子(STAT3 Transcription Factor);信号传导(Signal Transduction);熊脱氧胆酸(Ursodeoxycholic Acid)
DOI
10.3892/ijmm.2018.3807
PMID
30106087
发布时间
2019-01-02
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