Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex.

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作者： Alessandro A,Rizzo ^[1] ; Faye-Marie,Vassel ^[2] ; Nimrat,Chatterjee ^[2] ; Sanjay,D'Souza ^[2] ; Yunfeng,Li ^[1] ; Bing,Hao ^[1] ; Michael T,Hemann ^[2] ; Graham C,Walker ^[3] ; Dmitry M,Korzhnev ^[2]

作者单位： Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT 06030. ^[1] Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139. ^[2] The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139. ^[3] Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT 06030; korzhniev@uchc.edu. ^[4]

关键词 DNA damage tolerance HORMA domain proteins protein structure protein–protein interactions translesion synthesis

主题词细胞系(Cell Line);DNA损伤(DNA Damage);指导DNA的DNA聚合酶(DNA-Directed DNA Polymerase);人类(Humans);核蛋白质类(Nuclear Proteins);核苷酸基转移酶类(Nucleotidyltransferases);蛋白质多聚化(Protein Multimerization)

DOI 10.1073/pnas.1801149115

PMID 30111544

发布时间 2021-10-22

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