A New Hydrate of Cyclosporine: Structural and Physicochemical Characterization.

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作者： Ke,Wu ^[1] ; Anu,Gore ^[2] ; Richard,Graham ^[2]

作者单位： Pharmaceutical Development Department, Allergan Inc., Irvine, California 92612. Electronic address: wu_ke@allergan.com. ^[1] Pharmaceutical Development Department, Allergan Inc., Irvine, California 92612. ^[2]

关键词 Fourier-transform infrared spectroscopy (FTIR)cyclosporine (CsA)hydrate nonstoichiometric powder X-ray diffractometry (XRPD)single crystal X-ray diffraction (SCXRD)solid-state characterization solid-state nuclear resonance spectroscopy (SSNMR)solubility thermal analysis

主题词结晶学, X线(Crystallography, X-Ray);环孢菌素(Cyclosporine);免疫抑制剂(Immunosuppressive Agents);磁共振波谱学(Magnetic Resonance Spectroscopy);模型, 分子(Models, Molecular);粉末衍射(Powder Diffraction);溶解度(Solubility);谱学, 傅里叶变换红外(Spectroscopy, Fourier Transform Infrared);蒸汽(Steam);水(Water);X线衍射(X-Ray Diffraction)

DOI 10.1016/j.xphs.2018.08.002

PMID 30114405

发布时间 2019-08-16

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Journal of pharmaceutical sciences

2018年107卷12期

3070-3079页

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A New Hydrate of Cyclosporine: Structural and Physicochemical Characterization.

Journal of pharmaceutical sciences

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A New Hydrate of Cyclosporine: Structural and Physicochemical Characterization.

Journal of pharmaceutical sciences

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Journal of pharmaceutical sciences

相关期刊

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