Identification of Positively and Negatively Selected Driver Gene Mutations Associated With Colorectal Cancer With Microsatellite Instability.
第一作者:
Vincent,Jonchere
第一单位:
Sorbonne Université, University Pierre and Marie CURIE Paris 06, INSERM, Unité Mixte de Recherche938, Equipe Instabilité des Microsatellites et Cancer, Centre de Recherche Saint Antoine, Paris, France.
作者:
关键词
CRC, colorectal cancerColorectal CancerDriver Gene MutationsHR, hazard ratioMLH1, MutL Homolog 1MMR, mismatch repairMSH, MutS HomologMSI, microsatellite instabilityMicrosatellite InstabilityNR, nonrepetitivePBS, phosphate-buffered salinePCR, polymerase chain reactionPositive and Negative SelectionR, repetitiveRFS, relapse-free survivalRTCA, Real-Time Cell AnalyzerTumorigenic ProcessUTR, untranslated regionWES, whole-exome sequencingWGA, whole-genome amplificationbp, base pairindel, insertion/deletionmRNA, messenger RNAshRNA, short hairpin RNAsiRNA, small interfering RNA
主题词
动物(Animals);碱基序列(Base Sequence);细胞系, 肿瘤(Cell Line, Tumor);队列研究(Cohort Studies);结直肠肿瘤(Colorectal Neoplasms);女(雌)性(Female);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 裸(Mice, Nude);微卫星不稳定性(Microsatellite Instability);模型, 统计学(Models, Statistical);突变(Mutation);重复序列, 核酸(Repetitive Sequences, Nucleic Acid)
DOI
10.1016/j.jcmgh.2018.06.002
PMID
30116770
发布时间
2022-12-07
- 浏览16

Cellular and molecular gastroenterology and hepatology
2018年6卷3期
277-300页
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