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首页> BMC cancer> Malignant canine mammary epithelial cells shed exosomes containing differentially expressed microRNA that regulate oncogenic networks.

Malignant canine mammary epithelial cells shed exosomes containing differentially expressed microRNA that regulate oncogenic networks.

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作者： Eric J,Fish ^[1] ; Kristopher J,Irizarry ^[2] ; Patricia,DeInnocentes ^[3] ; Connor J,Ellis ^[2] ; Nripesh,Prasad ^[4] ; Anthony G,Moss ^[5] ; R,Curt Bird ^[3]

作者单位： Department of Pathobiology, College of Veterinary Medicine, Auburn University, 166 Greene Hall, Auburn, AL, 36849, USA. EJF0007@auburn.edu. ^[1] College of Veterinary Medicine, Western University of Health Sciences, Pomona, CA, 91766, USA. ^[2] Department of Pathobiology, College of Veterinary Medicine, Auburn University, 166 Greene Hall, Auburn, AL, 36849, USA. ^[3] Genomic Services Laboratory, Hudson Alpha Institute for Biotechnology, Huntsville, AL, 35806, USA. ^[4] Department of Biology, College of Science and Mathematics, Auburn University, Auburn, AL, 36849, USA. ^[5]

关键词 Bioinformatics Canine Deep-sequencing Estrogen receptor Exosomal Exosome Mammary cancer RNAseq Translational miR-18a microRNA

主题词动物(Animals);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);疾病模型, 动物(Disease Models, Animal);狗(Dogs);上皮细胞(Epithelial Cells);雌激素受体α(Estrogen Receptor alpha);外泌体(Exosomes);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因调控网络(Gene Regulatory Networks);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);乳房肿瘤, 动物(Mammary Neoplasms, Animal);微RNAs(MicroRNAs)

DOI 10.1186/s12885-018-4750-6

PMID 30126376

发布时间 2018-11-14

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BMC cancer

BMC cancer

2018年18卷1期

832页

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