SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts.-论文-万方医学网

第一作者： Anna,Beckmeyer-Borowko

第一单位： Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland. anna.borowko@gmail.com.;University of Basel, Basel, Switzerland. anna.borowko@gmail.com.

作者： Anna,Beckmeyer-Borowko ^[1] ; Medea,Imboden ^[2] ; Faisal I,Rezwan ^[3] ; Matthias,Wielscher ^[4] ; Andre F S,Amaral ^[5] ; Ayoung,Jeong ^[2] ; Emmanuel,Schaffner ^[2] ; Juha,Auvinen ^[6] ; Sylvain,Sebert ^[7] ; Ville,Karhunen ^[8] ; Robert,Bettschart ^[9] ; Alexander,Turk ^[10] ; Marco,Pons ^[11] ; Daiana,Stolz ^[12] ; Florian,Kronenberg ^[13] ; Ryan,Arathimos ^[14] ; Gemma C,Sharp ^[15] ; Caroline,Relton ^[14] ; Alexander J,Henderson ^[16] ; Marjo-Riitta,Jarvelin ^[17] ; Deborah,Jarvis ^[18] ; John W,Holloway ^[3] ; Nicole M,Probst-Hensch ^[19]

作者单位： Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland. anna.borowko@gmail.com.;University of Basel, Basel, Switzerland. anna.borowko@gmail.com. ^[1] Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland.;University of Basel, Basel, Switzerland. ^[2] Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK. ^[3] Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, W2 1PG, London, UK. ^[4] Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, W2 1PG, London, UK.;Population Health and Occupational Disease, NHLI, Imperial College London, London, UK. ^[5] Center for Life Course Health Research, University of Oulu, Oulu, Finland.;Oulunkaari Health Center, Ii, Finland.;Medical Research Center, University Hospital of Oulu, University of Oulu, Oulu, Finland. ^[6] Center for Life Course Health Research, University of Oulu, Oulu, Finland.;Biocenter Oulu, University of Oulu, Oulu, Finland.;Department for Genomics of Common Diseases, School of Public Health, Imperial College London, London, UK. ^[7] Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, W2 1PG, London, UK.;Center for Life Course Health Research, University of Oulu, Oulu, Finland. ^[8] Lungenpraxis Aarau, Hirslanden Klinik, Aarau, Switzerland. ^[9] Zürcher Höhenklinik, Wald, Switzerland. ^[10] Ospedale Regionale di Lugano-Sede Civico, Lugano, Switzerland. ^[11] Clinic of Pulmonary Medicine and Respiratory Cell Research, Basel, Switzerland. ^[12] Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria. ^[13] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.;Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. ^[14] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.;Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.;Bristol Dental School, University of Bristol, Bristol, UK. ^[15] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. ^[16] Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, W2 1PG, London, UK.;Center for Life Course Health Research, University of Oulu, Oulu, Finland.;Biocenter Oulu, University of Oulu, Oulu, Finland.;Unit of Primary Health Care, Oulu University Hospital, OYS, Kajaanintie 50, 90220, Oulu, Finland.;Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Kingston Lane, Uxbridge, Middlesex, UB8 3PH, UK. ^[17] Population Health and Occupational Disease, NHLI, Imperial College London, London, UK. ^[18] Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland. nicole.probst@swisstph.ch.;University of Basel, Basel, Switzerland. nicole.probst@swisstph.ch. ^[19]

医学主题词青少年(Adolescent);成年人(Adult);老年人(Aged);儿童(Child);儿童, 学龄前(Child, Preschool);队列研究(Cohort Studies);横断面研究(Cross-Sectional Studies);DNA甲基化(DNA Methylation);欧洲(Europe);女(雌)性(Female);人类(Humans);婴儿(Infant);婴儿, 新生(Infant, Newborn);纵向研究(Longitudinal Studies);肺(Lung);男(雄)性(Male);中年人(Middle Aged);人群监测(Population Surveillance);烟草烟污染(Tobacco Smoke Pollution);青年人(Young Adult);α1抗胰蛋白酶(alpha 1-Antitrypsin)

DOI 10.1186/s12931-018-0850-8

PMID 30134983

发布时间 2025-05-30

基金项目

R01 MH063706/MH/NIMH NIH HHS/United States G0600705/MRC_/Medical Research Council/United Kingdom G1002319/MRC_/Medical Research Council/United Kingdom MR/M013138/1/MRC_/Medical Research Council/United Kingdom MR/M022501/1/MRC_/Medical Research Council/United Kingdom WT_/Wellcome Trust/United Kingdom MR/M013138/2/MRC_/Medical Research Council/United Kingdom R01 HL087679/HL/NHLBI NIH HHS/United States MC_UU_00011/5/MRC_/Medical Research Council/United Kingdom RL1 MH083268/MH/NIMH NIH HHS/United States G9815508/MRC_/Medical Research Council/United Kingdom MC_UU_12013/2/MRC_/Medical Research Council/United Kingdom

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SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts.

Respiratory research

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SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts.

Respiratory research

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同项目论文

Respiratory research

相关期刊

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