Expedient Access to 2-Benzazepines by Palladium-Catalyzed C-H Activation: Identification of a Unique Hsp90 Inhibitor Scaffold.

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第一作者： Matteo,Virelli

第一单位： Department of Chemistry, University of Pavia, Viale Taramelli 10, 27100, Pavia, Italy.

作者： Matteo,Virelli ^[1] ; Elisabetta,Moroni ^[2] ; Giorgio,Colombo ^[1] ; Lorenzo,Fiengo ^[3] ; Alessio,Porta ^[4] ; Lutz,Ackermann ^[1] ; Giuseppe,Zanoni ^[1]

作者单位： Department of Chemistry, University of Pavia, Viale Taramelli 10, 27100, Pavia, Italy. ^[1] IRCCS MultiMedica, via Fantoli 16/15, 20138, Milano, Italy. ^[2] Istituto di Chimica del Riconoscimento Molecolare, CNR, Via Mario Bianco 9, 20131, Milano, Italy. ^[3] Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy. ^[4] Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077, Göttingen, Germany. ^[5]

关键词 C?H activation Hsp90 benzazepines docking analysis inhibitors

DOI 10.1002/chem.201804244

PMID 30136746

发布时间 2018-11-09

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