A PK/PD study of Delta-4 abiraterone metabolite in metastatic castration-resistant prostate cancer patients.

导出 LinkOut

翻译打印收藏纠错

作者： Benoit,Blanchet ^[1] ; Edith,Carton ^[2] ; Mohammad,Alyamani ^[3] ; Lisa,Golmard ^[4] ; Olivier,Huillard ^[2] ; Audrey,Thomas-Scheomann ^[5] ; Michel,Vidal ^[1] ; François,Goldwasser ^[2] ; Nima,Sharifi ^[3] ; Jérôme,Alexandre ^[6]

作者单位： Department of Pharmacokinetics and Pharmacochemisty, Hôpital Cochin, AP-HP, Paris, France; CARPEM, Paris, France; UMR8638 CNRS, Pharmacy UFR, University of Paris Descartes, PRES sorbonne Paris Cité, France. ^[1] Department of Medical Oncology, Hôpital Cochin, AP-HP, Paris, France; University of Paris Descartes, CARPEM, Paris, France. ^[2] Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. ^[3] Biopathology Department, Institut Curie, Paris, France. ^[4] UMR8638 CNRS, Pharmacy UFR, University of Paris Descartes, PRES sorbonne Paris Cité, France; Department of Clinical Pharmacy, Hôpital Cochin, AP-HP, Paris, France. ^[5] Department of Medical Oncology, Hôpital Cochin, AP-HP, Paris, France; University of Paris Descartes, CARPEM, Paris, France; Cochin Institute, INSERM U1016, Paris, France. Electronic address: jerome.alexandre@aphp.fr. ^[6]

关键词 Abiraterone Delta-4 abiraterone metabolite Pharmacokinetics Prostate cancer

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);雄激素受体拮抗剂(Androgen Receptor Antagonists);雄甾烯类(Androstenes);人类(Humans);男(雄)性(Male);存活率分析(Survival Analysis)

DOI 10.1016/j.phrs.2018.08.016

PMID 30142421

发布时间 2019-04-22

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交