Gastrin-releasing peptide receptor gene silencing inhibits the development of the epithelial-mesenchymal transition and formation of a calcium oxalate crystal in renal tubular epithelial cells in mice with kidney stones via the PI3K/Akt signaling pathway.
第一作者:
Xin-Fang,Wang
第一单位:
Department of Blood Purification, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
作者:
主题词
动物(Animals);草酸钙(Calcium Oxalate);细胞, 培养的(Cells, Cultured);结晶(Crystallization);疾病模型, 动物(Disease Models, Animal);上皮细胞(Epithelial Cells);上皮-间质转化(Epithelial-Mesenchymal Transition);肾结石(Kidney Calculi);肾小管(Kidney Tubules);小鼠, 近交C57BL(Mice, Inbred C57BL);磷酸肌醇3-激酶(Phosphatidylinositol 3-Kinase);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering);受体, 铃蟾肽(Receptors, Bombesin);信号传导(Signal Transduction)
DOI
10.1002/jcp.27023
PMID
30144073
发布时间
2022-02-23
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Journal of cellular physiology
1567-1577页
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