Increased expression of DRAM1 confers myocardial protection against ischemia via restoring autophagy flux.-论文-万方医学网

作者： Xiaoqian,Wu ^[1] ; Yuyan,Qin ^[2] ; Xiaoyan,Zhu ^[2] ; Dajun,Liu ^[3] ; Fajiang,Chen ^[2] ; Suowen,Xu ^[4] ; Dechong,Zheng ^[2] ; You,Zhou ^[2] ; Jiandong,Luo ^[5]

作者单位： Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University. Guangzhou, Guangdong 511436, PR China; Guangzhou Institute of Cardiovascular Disease, Guangzhou Key Laboratory of Cardiovascular Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, PR China. Electronic address: wuxiaoqian@gzhmu.edu.cn. ^[1] Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University. Guangzhou, Guangdong 511436, PR China. ^[2] Department of Nephrology, Shengjing Hospital of China Medical University, Shenyang 110036, China. ^[3] Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. ^[4] Key Laboratory of Molecular Clinical Pharmacology & Fifth Affiliated Hospital, Guangzhou Medical University. Guangzhou, Guangdong 511436, PR China; Guangzhou Institute of Cardiovascular Disease, Guangzhou Key Laboratory of Cardiovascular Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, PR China. Electronic address: jiandongluo@hotmail.com. ^[5]

主题词腺病毒科(Adenoviridae);动物(Animals);细胞凋亡(Apoptosis);自噬(Autophagy);细胞系(Cell Line);DNA甲基化(DNA Methylation);疾病模型, 动物(Disease Models, Animal);超声心动描记术(Echocardiography);基因表达谱(Gene Expression Profiling);基因表达调控(Gene Expression Regulation);遗传载体(Genetic Vectors);葡萄糖(Glucose);人类(Humans);男(雄)性(Male);膜蛋白质类(Membrane Proteins);心肌缺血(Myocardial Ischemia);肌细胞, 心脏(Myocytes, Cardiac);氧耗量(Oxygen Consumption);大鼠(Rats);转导, 遗传(Transduction, Genetic);心室重构(Ventricular Remodeling)

DOI 10.1016/j.yjmcc.2018.08.018

PMID 30144448

发布时间 2019-10-22

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Increased expression of DRAM1 confers myocardial protection against ischemia via restoring autophagy flux.

Journal of molecular and cellular cardiology

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Journal of molecular and cellular cardiology

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Increased expression of DRAM1 confers myocardial protection against ischemia via restoring autophagy flux.

Journal of molecular and cellular cardiology

相似文献

Journal of molecular and cellular cardiology

相关期刊

检索历史清除