Impaired cytolytic activity of asthma-associated natural killer cells is linked to dysregulated transcriptional program in energy metabolism.

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作者： Haisi,Wu ^[1] ; Jiacheng,Bi ^[2] ; Gaohui,Wu ^[3] ; Chaoyue,Zheng ^[4] ; Zhen,Lu ^[2] ; Lulu,Cui ^[2] ; Xiaochun,Wan ^[5]

作者单位： Shenzhen Laboratory of Antibody Engineering, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China; Department of Biotechnology, Guangxi Medical University, Nanning, China. ^[1] Shenzhen Laboratory of Antibody Engineering, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. ^[2] Department of Respiratory and Critical Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Shenzhen Luohu People's Hospital, The Third Affiliated Hospital of Shenzhen University, Shenzhen, China. ^[3] Shenzhen Laboratory of Antibody Engineering, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China; Jinan University, Guangzhou, China. ^[4] Shenzhen Laboratory of Antibody Engineering, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic address: xc.wan@siat.ac.cn. ^[5]

关键词 Allergic diseases Dysfunction Exhaustion Metabolism Natural killer cells