Type 2 diabetes-associated variants of the MT<sub>2</sub> melatonin receptor affect distinct modes of signaling.

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第一作者： Angeliki,Karamitri

第一单位： Inserm, U1016, Institut Cochin, Paris, France.

作者： Angeliki,Karamitri ^[1] ; Bianca,Plouffe ^[2] ; Amélie,Bonnefond ^[3] ; Min,Chen ^[4] ; Jonathan,Gallion ^[5] ; Jean-Luc,Guillaume ^[1] ; Alan,Hegron ^[2] ; Mathilde,Boissel ^[3] ; Mickaël,Canouil ^[6] ; Claudia,Langenberg ^[1] ; Nicholas J,Wareham ^[2] ; Christian,Le Gouill ^[3] ; Viktoria,Lukasheva ^[1] ; Olivier,Lichtarge ^[2] ; Philippe,Froguel ^[3] ; Michel,Bouvier ^[5] ; Ralf,Jockers ^[5]

作者单位： Inserm, U1016, Institut Cochin, Paris, France. ^[1] CNRS UMR 8104, Paris, France. ^[2] Université Paris Descartes, Paris, France. ^[3] Institute for Research in Immunology and Cancer and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montreal, Québec H3C 3J7, Canada. ^[4] Université Lille, CNRS UMR 8199-EGID, Institut Pasteur de Lille, Lille, France. ^[5] Structural Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX 77030, USA. ^[6] Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK. ^[7] Université Lille, CNRS UMR 8199-EGID, Institut Pasteur de Lille, Lille, France. ralf.jockers@inserm.fr michel.bouvier@umontreal.ca philippe.froguel@cnrs.fr. ^[8] Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, W12 0NN London, UK. ^[9] Institute for Research in Immunology and Cancer and Department of Biochemistry and Molecular Medicine, Université de Montréal, Montreal, Québec H3C 3J7, Canada. ralf.jockers@inserm.fr michel.bouvier@umontreal.ca philippe.froguel@cnrs.fr. ^[10] Inserm, U1016, Institut Cochin, Paris, France. ralf.jockers@inserm.fr michel.bouvier@umontreal.ca philippe.froguel@cnrs.fr. ^[11]