Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria.

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第一作者： Samuel J,Balin

第一单位： Division of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.

作者： Samuel J,Balin ^[1] ; Matteo,Pellegrini ^[2] ; Eynav,Klechevsky ^[3] ; Sohui T,Won ^[4] ; David I,Weiss ^[2] ; Aaron W,Choi ^[5] ; Joshua,Hakimian ^[2] ; Jing,Lu ^[2] ; Maria Teresa,Ochoa ^[3] ; Barry R,Bloom ^[6] ; Lewis L,Lanier ^[7] ; Steffen,Stenger ^[8] ; Robert L,Modlin ^[9]

作者单位： Division of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. ^[1] Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. ^[2] Molecular Cell and Developmental Biology at UCLA, Los Angeles, CA 90095, USA. ^[3] Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63108, USA. ^[4] Molecular Biology Interdepartmental Graduate Program, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. ^[5] Department of Dermatology, University of Southern California School of Medicine, Los Angeles, CA 90033, USA. ^[6] Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. ^[7] Department of Microbiology and Immunology and the Parker Institute for Cancer Immunotherapy, University of California, San Francisco, San Francisco, CA 94143, USA. ^[8] Institute for Medical Microbiology and Hygiene, University Hospital Ulm, Ulm, Germany. ^[9] Division of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. rmodlin@mednet.ucla.edu. ^[10]

主题词抗原, 分化, T淋巴细胞(Antigens, Differentiation, T-Lymphocyte);细胞因子类(Cytokines);颗粒酶类(Granzymes);人类(Humans);麻风(Leprosy);鼠麻风分枝杆菌(Mycobacterium lepraemurium);穿孔素(Perforin);受体, 自然杀伤细胞(Receptors, Natural Killer Cell);T淋巴细胞, 细胞毒性(T-Lymphocytes, Cytotoxic)

DOI 10.1126/sciimmunol.aat7668

PMID 30171080

发布时间 2020-03-09

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Science immunology

2018年3卷26期

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Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria.

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Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria.

Science immunology

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Science immunology

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