Melatonin mediated Foxp3-downregulation decreases cytokines production via the TLR2 and TLR4 pathways in H. pylori infected mice.

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第一作者： Jianhua,Luo

第一单位： Key Laboratory of Ministry of Education for Gastrointestinal Cancer, PR China; School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, PR China.

作者： Jianhua,Luo ^[1] ; Jun,Song ^[2] ; Hui,Zhang ^[3] ; Feng,Zhang ^[1] ; Hui,Liu ^[4] ; Li,Li ^[5] ; Zhiguang,Zhang ^[5] ; Lushan,Chen ^[6] ; Mi,Zhang ^[1] ; Dacen,Lin ^[1] ; Meifang,Lin ^[1] ; Ruixiang,Zhou ^[7]

作者单位： Key Laboratory of Ministry of Education for Gastrointestinal Cancer, PR China; School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, PR China. ^[1] Department of Cell Biology and Genetics, PR China; School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, PR China. ^[2] Fujian Center for Safety Evaluation of New Drugs, PR China; School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, PR China. ^[3] Department of Human Anatomy, Histology and Embryology, PR China; School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, PR China. ^[4] Key Laboratory of Ministry of Education for Gastrointestinal Cancer, PR China; Department of Cell Biology and Genetics, PR China; School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, PR China. ^[5] Key Laboratory of Ministry of Education for Gastrointestinal Cancer, PR China; Department of Pathology, Union Hospital, PR China; School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, PR China. ^[6] Key Laboratory of Ministry of Education for Gastrointestinal Cancer, PR China; Department of Human Anatomy, Histology and Embryology, PR China; School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, PR China. Electronic address: rxzhou@fjmu.edu.cn. ^[7]

关键词 Foxp3 H. pylori MAPK Melatonin NF-κ B TLR2 TLR4

主题词动物(Animals);细胞因子类(Cytokines);减量调节(Down-Regulation);叉头转录因子类(Forkhead Transcription Factors);胃炎(Gastritis);螺杆菌感染(Helicobacter Infections);幽门螺杆菌(Helicobacter pylori);褪黑激素(Melatonin);小鼠(Mice);NF-κB(NF-kappa B);Toll样受体2(Toll-Like Receptor 2);Toll样受体4(Toll-Like Receptor 4);转化生长因子β1(Transforming Growth Factor beta1)

DOI 10.1016/j.intimp.2018.08.034

PMID 30173051

发布时间 2019-02-22

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International immunopharmacology

2018年64卷

116-122页

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Melatonin mediated Foxp3-downregulation decreases cytokines production via the TLR2 and TLR4 pathways in H. pylori infected mice.

International immunopharmacology

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International immunopharmacology

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Melatonin mediated Foxp3-downregulation decreases cytokines production via the TLR2 and TLR4 pathways in H. pylori infected mice.

International immunopharmacology

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International immunopharmacology

相关期刊

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