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首页> Analytica chimica acta> Ultrasensitive quantitative detection of small molecules with rapid lateral-flow assay based on high-affinity bifunctional ligand and magnetic nanolabels.

Ultrasensitive quantitative detection of small molecules with rapid lateral-flow assay based on high-affinity bifunctional ligand and magnetic nanolabels.

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作者： Sergey L,Znoyko ^[1] ; Alexey V,Orlov ^[2] ; Averyan V,Pushkarev ^[2] ; Elizaveta N,Mochalova ^[2] ; Natalia V,Guteneva ^[2] ; Afanasy V,Lunin ^[3] ; Maxim P,Nikitin ^[2] ; Petr I,Nikitin ^[4]

作者单位： Prokhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilov St, Moscow, 119991, Russia. ^[1] Prokhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilov St, Moscow, 119991, Russia; Moscow Institute of Physics and Technology, 9 Institutskii per, Dolgoprudny, Moscow Region, 141700, Russia. ^[2] Moscow Institute of Physics and Technology, 9 Institutskii per, Dolgoprudny, Moscow Region, 141700, Russia. ^[3] Prokhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilov St, Moscow, 119991, Russia; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), 31 Kashirskoe shosse, Moscow, 115409, Russia. Electronic address: nikitin@kapella.gpi.ru. ^[4]

关键词 Biosensing Low-molecular substances Magnetic nanoparticles Real-time monitoring of biomolecular binding Small molecules detection Ultrasensitive immunoassay

主题词抗体, 单克隆(Antibodies, Monoclonal);生物素(Biotin);色谱法, 亲和(Chromatography, Affinity);人类(Humans);配体(Ligands);磁性纳米粒子(Magnetite Nanoparticles);小分子化合物库(Small Molecule Libraries);甲状腺素(Thyroxine)

DOI 10.1016/j.aca.2018.07.012

PMID 30193630

发布时间 2018-12-18

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