Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response.

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作者： Yasuhiro,Uchimura ^[1] ; Tobias,Fuhrer ^[2] ; Hai,Li ^[3] ; Melissa A,Lawson ^[3] ; Michael,Zimmermann ^[2] ; Bahtiyar,Yilmaz ^[3] ; Joel,Zindel ^[3] ; Francesca,Ronchi ^[3] ; Marcel,Sorribas ^[3] ; Siegfried,Hapfelmeier ^[4] ; Stephanie C,Ganal-Vonarburg ^[3] ; Mercedes,Gomez de Agüero ^[3] ; Kathy D,McCoy ^[3] ; Uwe,Sauer ^[5] ; Andrew J,Macpherson ^[6]

作者单位： Maurice Müller Laboratories (Department of Biomedical Research), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Murtenstrasse 35, University of Bern, 3008 Bern, Switzerland; Department of Anatomy and Cell Biology, Shiga University of Medical Science, 520-2192 Shiga, Japan. ^[1] Institute of Molecular Systems Biology, Swiss Federal Institute of Technology (ETH) Zürich, Zürich, Switzerland. ^[2] Maurice Müller Laboratories (Department of Biomedical Research), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Murtenstrasse 35, University of Bern, 3008 Bern, Switzerland. ^[3] Institute for Infectious Diseases, University of Bern, Bern, Switzerland. ^[4] Institute of Molecular Systems Biology, Swiss Federal Institute of Technology (ETH) Zürich, Zürich, Switzerland. Electronic address: sauer@imsb.biol.ethz.ch. ^[5] Maurice Müller Laboratories (Department of Biomedical Research), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Murtenstrasse 35, University of Bern, 3008 Bern, Switzerland. Electronic address: andrew.macpherson@insel.ch. ^[6]

关键词 (13)C-isotope tracing IgA colonization germ free inflammation intestinal transit lipidemia metabolomics microbial metabolites microbiota