换一批
换一批Polyphyllin I Inhibits Proliferation and Induces Apoptosis by Downregulating AML1-ETO and Suppressing C-KIT/Akt Signaling in t(8;21) Acute Myeloid Leukemia.
第一作者：
Yanting,Chai
第一单位：
Child Health Center, Shiyan Maternal and Child Health Hospital, Shiyan, 442000, P. R. China.
作者：
主题词
抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);细胞凋亡(Apoptosis);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);染色体, 人, 21对(Chromosomes, Human, Pair 21);染色体, 人, 8对(Chromosomes, Human, Pair 8);核心结合因子α2亚基(Core Binding Factor Alpha 2 Subunit);薯蓣皂甙配基(Diosgenin);剂量效应关系, 药物(Dose-Response Relationship, Drug);减量调节(Down-Regulation);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);人类(Humans);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);医学, 中国传统(Medicine, Chinese Traditional);分子构象(Molecular Conformation);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);原癌基因蛋白质类c-kit(Proto-Oncogene Proteins c-kit);信号传导(Signal Transduction);构效关系(Structure-Activity Relationship);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1002/cbdv.201800314
PMID
30194712
发布时间
2018-12-21
- 浏览6
Chemistry & biodiversity
e1800314页
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